Cell structure and proliferation: Tyrosine Phosphatase Pez
PTP-Pez is a FERM domain-containing scaffold protein that is conserved from flies to humans. It acts as a tumor suppressor in the Hippo/Yorkie pathway. See:
Poernbacher I, Baumgartner R, Marada SK, Edwards K, and Stocker H. 2012. Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation. Current Biology
22:389-96. doi: 10.1016/j.cub.2012.01.019 [PMID:22305752]
Bretscher, A., K. Edwards, and R.G. Fehon. 2002. ERM proteins and merlin: integrators at the cell cortex. Nature Reviews Molecular Cell Biol.
3:586-599. [Review] [PMID: 12154370]
Edwards, K.A., T. Davis, D. Marcey, J. Kurihara, and D. Yamamoto. 2001. Comparative analysis of the Band 4.1/ezrin-related protein tyrosine phosphatase Pez from two Drosophila species: implications for structure and function. Gene
275:195-205. [PMID: 11587846]