Thompson, C.F., K.E. Hodges, N.T. Mortimer, A.D. Vrailas-Mortimer, S.K. Sakaluk, M.E. Hauber. 2022. Avian eggshell coloration predicts shell-matrix protoporphyrin content. Canadian J of Zoology, 100: 77-81. doi: 10.1139/cjz-2021-0134.
Mortimer, N.T., M.L. Fischer, A.L. Waring, P. Kr, B.Z. Kacsoh, S.E. Brantley, E.S. Keebaugh, J. Hill, C. Lark, J. Martin, P. Bains, J. Lee, A.D. Vrailas-Mortimer, T.A. Schlenke. 2021. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster. PNAS, 118 (39): e2017460118.
News feature: What Mutant Flies Can Teach Us About Autoimmune Disorders
Write up in the Pantagraph: ISU Lab Explores Flies and Autoimmune Disorders
Ryan, S. M., M. Almassey, A.M. Burch, G. Ngo, J.M. Martin, D. Myers, D. Compton, S. Archie, L. Naeger, A. Salzman, A. Virola-Iarussi, M. Cross, S. Barbee, N.T. Mortimer, S. Sanyal, A. D. Vrailas-Mortimer. Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis. Aging Cell, 20 (11): e13481.
Available on bioRxiv: doi.org/10.1101/552729.
Calderon, S.J., S.Y. Chung, C.J. Fields, N.T. Mortimer. 2021. Children Tooth Brushing Behavior and Oral Microbiota: A Pilot Study. Oral, 1(2): 112-121.
Kr, P., J. Lee, N.T. Mortimer. 2021. The S1A protease family members CG10764 and CG4793 regulate cellular immunity in Drosophila. microPublication Biology: 10.17912/micropub.biology.000370.
Trainor, J.E., P. Kr, N.T. Mortimer. 2021. Immune Cell Production Is Targeted by Parasitoid Wasp Virulence in a Drosophila–Parasitoid Wasp Interaction. Pathogens, 10(1): 49.
Available on bioRxiv: doi.org/10.1101/2020.12.01.406736
Ryan, S.M., K. Wildman, B. Oceguera-Perez, S. Barbee, N.T. Mortimer, A. Vrailas-Mortimer. 2020. Evolutionarily conserved transcription factors drive the oxidative stress response in Drosophila. Journal of Experimental Biology, 223(14): jeb221622.
Available on bioRxiv: doi.org/10.1101/735126
Sargent, L., Y. Liu, W. Leung, N.T. Mortimer, D. Lopatto, J. Goecks, S.C.R. Elgin. 2020. G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation. PLoS Computational Biology, 16(6): e1007863.
Available on bioRxiv: doi.org/10.1101/781658
Hodges, K.E., N.T Mortimer, A.D. Vrailas-Mortimer, S.K. Sakaluk, C.F. Thompson. 2020. Connecting the dots: avian eggshell pigmentation, female condition and paternal provisioning effort. Biological Journal of the Linnean Society, 130(1): 114-127.
Lopatto, D., et al. 2020. Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience. J. Microbiol Biol Educ, 21(1): 21.1.6.
Alvarado, G., S.R. Holland, J. DePerez-Rasmussen, B.A. Jarvis, T. Telander, N. Wagner, A.L. Waring, A. Anast, B. Davis, A. Frank, K. Genenbacher, J. Larson, C. Mathis, A.E. Oates, N.A. Rhoades, L. Scott, J. Young, N.T. Mortimer. 2020. Bioinformatic analysis suggests potential mechanisms underlying parasitoid venom evolution and function. Genomics, 112: 1096-1104.
Available on bioRxiv: doi.org/10.1101/423343
Leung, W. et al. 2017. Retrotransposons are the major contributors to the expansion of the Drosophila ananassae Muller F element. G3: Genes, Genomics, Genetics 7(8): 2439-2460.
Schachtner, L.T., I.E. Sola, D. Forand, S. Antonacci, A.J. Postovit, N.T. Mortimer, D.J. Killian, E.C. Olesnicky. 2015. Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development. Development Genes and Evolution, 225(6): 319-330.
Antonacci, S., D. Forand, M. Wolf, C. Tyus, J. Barney, L. Kellogg, M. Simon, G. Kerr, N.T. Mortimer, E.C. Olesnicky, D.J. Killian. 2015. Conserved RNA-Binding Proteins are Required for Dendrite Morphogenesis in Caenorhabditis elegans Sensory Neurons. G3: Genes, Genomics, Genetics 5(4): 639-53.
Vrailas-Mortimer, A., S.M. Ryan, M.J. Avey, N.T. Mortimer, H. Dowse, S. Sanyal. 2014. p38 MAP Kinase regulates circadian rhythms in Drosophila. Journal of Biological Rhythms 29(6): 411-426.
Mortimer, N.T., J. Goecks, B.Z. Kacsoh, J.A. Mobley, G.J. Bowersock, J. Taylor, T.A. Schlenke. 2013. Parasitoid wasp venom SERCA regulates Drosophila calcium levels and inhibits cellular immunity. Proceedings of the National Academy of Sciences USA (PNAS) 110(23): 9427-9432.
Featured in: Science Signaling, The Journal of Experimental Biology, and Science Daily.
Goecks, J., N.T. Mortimer, J.A. Mobley, G.J. Bowersock, J. Taylor, T.A. Schlenke. 2013. Integrative approach reveals composition of endoparasitoid wasp venoms. PLOS One 8(5): e64125.
Kacsoh, B.Z., Z.R. Lynch, N.T. Mortimer, T.A. Schlenke. 2013. Fruit flies medicate offspring after seeing parasites. Science 339(6122): 947-950.
Featured in: The Naked Scientists, National Geographic, and Live Science.
Mortimer, N.T., K.H. Moberg. 2013. The archipelago ubiquitin ligase subunit acts in target tissue to restrict tracheal terminal cell branching and hypoxic-induced gene expression. PLOS Genetics 9(2): e1003314.
Mortimer, N.T., B.Z. Kacsoh, E.S. Keebaugh, T.A. Schlenke. 2012. Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. PLOS Pathogens 8(7): e1002819.
Mortimer, N.T., K.H. Moberg. 2009. Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia. Developmental Biology 329(2): 294-305.
Mortimer, N.T., K.H. Moberg. 2007. The Drosophila F-box protein Archipelago controls levels of the Trachealess transcription factor in the embryonic tracheal system. Developmental Biology 312(2): 560-571.
Suli, A., N.T. Mortimer, I. Shepherd, C.B. Chien. 2006. Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons. Journal of Neuroscience 26(51): 13328-13337.
Rogers, E.M., C.A. Brennan, N.T. Mortimer, S. Cook, A.R. Morris, K. Moses. 2005. Pointed regulates an eye-specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow. Development 132(21): 4833-4843.
Yedvobnick, B., A. Kumar, P. Chaudhury, J. Opraseuth, N.T. Mortimer, K.M. Bhat. 2004. Differential effects of Drosophila mastermind on asymmetric cell fate specification and neuroblast formation. Genetics 166(3): 1281-1289.
Invited Reviews
Elgin, S.C.R., The Genomics Education Partnership. 2017. The GEP: Crowd-Sourcing Big Data with Undergraduates. Trends in Genetics 33(2): 81-85.
Mortimer, N.T. 2013. Parasitoid wasp virulence: a window into fly immunity. Fly 7(4): 242-248.
Preprints
Kr, P., N.T. Mortimer. Loss of self-tolerance leads to altered gene expression and IMD pathway activation in Drosophila melanogaster. bioRxiv: doi.org/10.1101/2021.11.19.469298.
Waring, A.L., J. Hill, B.M. Allen, N.M. Bretz, N. Le, P. Kr, D. Fuss, N.T. Mortimer. Meta-analysis of immune induced gene expression changes in diverse Drosophila melanogaster innate immune responses. bioRxiv: doi.org/10.1101/2021.09.23.461556.
Sultana, S., K. LeDoux, M.E. Crompton, O. Jankiewicz, G.H. Morales, C. Johnson, E. Horbach, K.P. Hoffmann, P. KR, R. Shah, G.M. Anderson, N.T. Mortimer, J.E. Schmitz, M. Hadjifrangiskou, A. Foti, J.U. Dahl. Redox-mediated inactivation of the transcriptional repressor C3600 makes uropathogenic Escherichia coli exquisitely resistant to reactive chlorine species. bioRxiv: doi.org/10.1101/2021.08.31.458474.
Brantley, S.E., N.T. Mortimer, T.A. Schlenke. Host JAK/Stat activity is a target of endoparasitoid wasp virulence strategies. bioRxiv: doi.org/10.1101/423335.