Fly Tyrosine Kinase and PTP Lists

Complete tyrosine kinase list for Drosophila melanogaster​

Abbreviation	Full gene name	CG number	FlyBase record
Abl	Abl tyrosine kinase	CG4032	FBgn0000017
Ack	Ack	CG14992	FBgn0028484
Alk	Alk	CG8250	FBgn0040505
Btk29A	Btk family kinase at 29A	CG8049	FBgn0003502
btl	breathless	CG32134	FBgn0005592
Cad96Ca	Cad96Ca	CG10244	FBgn0022800
CG3277	CG3277 (note: PDGFR-related)	CG3277	FBgn0031518
Csk	C-terminal Src kinase	CG17309	FBgn0037925
Ddr	Discoidin domain receptor	CG33531	FBgn0053531
dnt	doughnut on 2	CG17559	FBgn0024245
drl	derailed	CG17348	FBgn0015380
Drl-2	Derailed 2	CG3915	FBgn0033791
Egfr	Epidermal growth factor receptor	CG10079	FBgn0003731
Eph	Eph receptor tyrosine kinase	CG1511	FBgn0025936
Fak56D	Focal Adhesion Kinase	CG10023	FBgn0020440
Fps85D	Fps oncogene analog	CG8874	FBgn0000723
hop	hopscotch	CG1594	FBgn0004864
htl	heartless	CG7223	FBgn0010389
InR	Insulin-like receptor	CG18402	FBgn0013984
Nrk	Neurospecific receptor kinase	CG4007	FBgn0020391
otk	off-track	CG8967	FBgn0004839
PR2	Fak-like tyrosine kinase	CG3969	FBgn0013955
Pvr	PDGF- and VEGF-receptor related	CG8222	FBgn0032006
Ret	Ret oncogene	CG14396	FBgn0011829
Ror	Ror	CG4926	FBgn0010407
sev	sevenless	CG18085	FBgn0003366
shark	Src homology 2, ankyrin repeat, tyrosine kinase	CG18247	FBgn0015295
Src42A	Src oncogene at 42A	CG7873	FBgn0004603
Src64B	Src oncogene at 64B	CG7524	FBgn0003501
Tie	Tie-like receptor tyrosine kinase	CG7525	FBgn0014073
tor	torso	CG1389	FBgn0003733
Wsck	Wsck	CG31127	FBgn0046685

This table presents the complete, nonredundant set of standard tyrosine-specific kinases in D. melanogaster. A total of 32 tyrosine kinase genes were identified by an exhaustive BLAST analysis of Drosophila coding regions using several known tyrosine kinases as “probes”. The list does not include dual-specificity kinases.

Complete tyrosine phosphatase list for Drosophila melanogaster​

Abbreviation	Full gene name/comments​	CG number	FlyBase record	Type
CG14297	CG14297	CG14297	FBgn0038655	Low MW PTP
CG31469	CG31469	CG31469	FBgn0051469	Low MW PTP
primo-1	primo-1	CG33748	FBgn0040077	Low MW PTP
primo-2	primo-2	CG33747	FBgn0040076	Low MW PTP
CG9311	CG9311  (non-receptor type 23; TD14 homologue; N-terminal BRO1 domain)	CG9311	FBgn0036448	Standard PTP
Pez	Pez (FERM-PTP/PEZ class; non-receptor type 14 & 21; PTP36, PTP-Pez/D2 and PTP-D1 homologue)	CG9493	FBgn0031799	Standard PTP
Ptpmeg	Ptpmeg (FERM-PTP/MEG class; non-receptor type 3 & 4; PTP-Meg1 and PTP-H1 homologue)	CG1228	FBgn0035133	Standard PTP
csw	corkscrew	CG3954	FBgn0000382	Standard PTP
Ptp61F	Protein tyrosine phosphatase 61F	CG9181	FBgn0003138	Standard PTP
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	CG9856	FBgn0016641	Standard PTP
l(1)G0232	lethal (1) G0232 (non-receptor type 9; PTP-Meg2 homologue)	CG32697	FBgn0028341	Standard PTP
Ptp4E	Protein tyrosine phosphatase 4E	CG6899	FBgn0004368	Standard PTP
Ptp10D	Protein tyrosine phosphatase 10D	CG1817	FBgn0004370	Standard PTP
Ptp52F	Ptp52F	CG18243	FBgn0034085	Standard PTP
Ptp69D	Protein tyrosine phosphatase 69D	CG10975	FBgn0014007	Standard PTP
Ptp99A	Protein tyrosine phosphatase 99A	CG11516	FBgn0004369	Standard PTP
Lar	Leukocyte-antigen-related-like	CG10443	FBgn0000464	Standard PTP
CG14714	CG14714 (should be merged to CG14713?)	CG14714	FBgn0037929	Standard PTP
CG7180	CG7180 (R-PTP-kappa homologue)	CG7180	FBgn0032673	Standard PTP
ia2	ia2 (R-PTP-N2 homologue)	CG31795	FBgn0031294	Standard PTP
eya	eyes absent	CG9554	FBgn0000320	Non-standard PTP