Research

Lay summary: The activity of proteins mediating biological processes has to be tightly regulated to achieve homeostasis (maintenance of a stable and balanced internal environment). We study the function of motor proteins, tiny molecular scale transporters, in building and a specialized structure called the primary cilium, protruding from most cells of the human body. Malfunctioning cilia are associated with many human diseases. On a molecular level, we study how the activity of the motor proteins is regulated, what kind of cargo they carry, and how they contribute to building and maintaining the ciliary structure..